Formulations of protective cosmetic products obtained by applying integrated and sustainable bioeconomy approaches
BioProtect
PN-III-P2-2.1-PED-2021-0273
(644PED/2022)
Chronic exposure of human skin to solar UV radiation is widely recognized as the key factor responsible for photo-ageing. For these reasons, the role of photoprotection is critical to avoid skin cancer and others undesired effects.
Contracting authority: Executive Unit for Financing Higher Education, Research, Development and Innovation (UEFISCDI)
Implementation period: 21/06/2022-20/06/2024
Budget: 598.795 lei
Project director: Dr. Habil. Irina Fierăscu
Coordinator:
National Institute for Research & Development in Chemistry and Petrochemistry – ICECHIM Bucharest
Project director: Dr. Habil. Irina Fierăscu
Partner:
University POLITEHNICA of Bucharest,
Partner responsible: Dr. Eng. Aurelian Cristian Boscornea
The BioProtect project proposes the use of nanomaterials both as active ingredient and delivery system of bioactive compounds (mixtures of phenolic compounds – rutin and quercitin) recovered from grape by-products for development of UV blocking cosmetic products. Target molecules obtained through green technologies from grapes by-products can be used as potential active UV blockers in cosmetic formulations being delivered by apatitic materials.
Development of synthesis methods for the delivery system and adaptation of extraction methods for grape by-products.
Implementation period: 21/06/2022 – 31/12/2022
Activities:
Development of the technology for obtaining sunscreen formulations with active delivery system and natural compounds.
Implementation period: 01/01/2023 – 31/12/2023
Activities:
Demonstration and validation of the proposed solutions
Implementation period: 01/01/2024 – 20/06/2024
Activities:
Published papers
Book chapters
Workshop
Patent application
Scientific meetings
Institutional & individual awards
Development of synthesis methods for the delivery system and adaptation of extraction methods for grape by-products
Summary
The grape industry, especially the wine industry, generates nutrient-rich by-products that are underutilized and often end up polluting the environment. After the extraction of grape juice, the remaining materials are currently not valued as highly profitable waste, being mainly dumped in open spaces, thus causing environmental problems.
In this context, the general objective of the project “Formulation of protective cosmetic products obtained by applying integrated and sustainable strategies of the bioeconomy – BIOProtect” is to propose the use of nanomaterials both as an active ingredient and as a system of delivery of bioactive compounds recovered from the by-products of the grape industry, for the development of cosmetic products, the target molecules obtained through green technologies being used as potential active UV blockers in cosmetic formulations that are “transported” by means of substituted hydroxyapatite.
The activities planned to be carried out by the partners during the first year of implementation were:
The deliverables assumed by the financing contract for Phase 1 of the project were completed in full, as follows:
The obtained results were disseminated within the scientific community (1 paper published in Q1/Q2 ISI journal, 3 participations in international conferences, participation in trade fairs and exhibitions of invention and innovation), the dissemination results being widely presented on the project website (Romanian version – https://icechim.ro/project/bioprotect_ro/, English version – https://icechim.ro/project/bioprotect_en/); the project was also promoted through the newsletter weekly of the Ministry of Research, Innovation and Digitization (https://research.gov.ro/uploads/comunicare/buletin-informativ/2022/buletin-informativ-mcid-nr-43.pdf).
The proposed activities were carried out in full, supporting the continuation of the project in 2023.
Development of the technology to obtain sunscreen formulations with active delivery system and natural compounds.
Summary
Chronic exposure of human skin to solar UV radiation is widely recognized as the main factor responsible for photoaging. For these reasons, the role of protection is essential to avoid skin cancer and other unwanted effects.
The aim of the BioProtect project is to propose the use of nanomaterials both as an active ingredient and as a delivery system for bioactive compounds (mixtures of phenolic compounds – rutin and quercitin) recovered from grape by-products for the development of cosmetic products with UV blocking properties.
The activities planned to be carried out by the partners during the 2nd stage of project implementation were:.
The deliverables proposed by the request and the financing contract for Stage 2 of the project were fully achieved (and even exceeded), as follows: Report on the properties of UV blocking for active delivery systems; Report on UV Blocking Properties for Natural Compounds; Report on UV Blocker Properties for Active Delivery Systems – Natural Compounds; Report on the characterization of the obtained cosmetic formulation; The second economic and scientific report to the Contracting Authority; papers in the ISI rated journal; participation in 2023; Workshop.
The obtained results were disseminated within the scientific community, being widely presented on the project website (Romanian version – https://icechim.ro/project/bioprotect_ro/, English version – https://icechim.ro /project/bioprotect_en/).
The proposed scientific activities were carried out in full, supporting the continuation of the project in 2024..
The degree of achievement of the objectives
No | Estimated result | Achieved result |
---|---|---|
1 | Report on UV blocking properties for active delivery systems | The property evaluation report for the delivery systems (apatitic compounds – hydroxyapatite and iron-hydroxyapatite) was made. |
2 | Report on UV blocking properties for natural compounds | The property evaluation report for the natural compounds obtained from viticulture wastes was made |
3 | Report on UV Blocker Properties for Active Delivery Systems – Natural Compounds | The property evaluation report for the delivery systems – natural compounds was made |
4 | Report on the characterization of the obtained cosmetic formulation | The characterization report was made for cosmetic formulations based on natural compounds, FeHaP-natural compounds hybrid systems, but also alternative solutions of metal nanoparticles |
5 | Submission for publication of at least two ISI articles in Q1/Q2 journals | 2 ISI articles were published in Q1/Q2 journals and 1 article in a Q4 journal, 1 article sent for evaluation in Q1 journals |
6 | Participation in at least 3 scientific events | 14 participations in international scientific events were recorded (9 at scientific conferences and 5 at invention exhibitions) |
7 | Workshop organization | Development of protective cosmetic products through bioeconomy approaches (11.10.2023), within the “Priorities of Chemistry for a Sustainable Development” PRIOCHEM XIXth Edition, 11-13 October 2023, Bucharest |
8 | – | Patent application A0375/2023 was submitted |
9 | Project web page | The project website has been updated, both in Romanian and in English |