Antimicrobial nanocomposites based on polyurethane foam for biomedical applications, synthesized by radiation assisted technology

PuMA

PN-III-P2-2.1-PED-2021-0423

(612PED/2022)

The new materials to be synthesized in this project are innovative metallic nanoparticles uniformly dispersed in polyurethane foam (PU).

Project goal

The project goal is to develop some composite materials with intrinsic antimicrobial properties and to characterize their functionality.

Contracting authority: Executive Unit for Financing Higher Education, Research, Development and Innovation (UEFISCDI)

Implementation period: 25/06/2022-24/06/2024

Budget: 179.639 lei

Project responsible: Dr. Habil. Radu Claudiu Fierăscu

  • Consortium
  • General objective
  • Phase I
  • Phase II
  • Phase III
  • Results dissemination
Consortium
General objective

The aim of the project is to prepare some composite materials with intrinsic antimicrobial properties and to characterize their functionality. The new materials to be synthesized in this project are innovative metallic nanoparticles uniformly dispersed in polyurethane foam (PU).

Phase I

Establishment of parameters for obtaining polyurethane foam composites with AgNP and / or CuNP. Preliminary obtaining experiments.

Implementation period: 25/06/2022 – 31/12/2022

Activities of the ICECHIM partner:

  • Study of physico-chemical methods for testing composites based on polyurethane foam (PU);
  • Defining the parameters of PU/ metallic nanoparticles (MeNP) composites depending on the shape, size and stability of metal nanoparticles;
  • Results dissemination.
Phase II

Characterization of experimental models (EM) of PU/MeNPs foam. Obtaining functional models (FM) of PU/MeNPs foam.

Implementation period: 01/01/2023 – 31/12/2023

Activities of the ICECHIM partner:

  • Physico-chemical characterization of selected EM of PU/MeNPs foam;
  • Physico-chemical characterization of FM of PU/MeNPs foam;
  • Results dissemination.
Phase III

Laboratory technology for obtaining PU/MeNPs foam composites with biomedical applications

Implementation period: 01/01/2024 – 24/06/2024

Activities of the ICECHIM partner:

  • Migration/release tests of metallic nanoparticles from PU/MeNP composites;
  • Development and validation of laboratory technology;
  • Development of technical documentation for laboratory technology;
  • Results dissemination.
Results dissemination

ISI Papers

  1. Metal and metal oxide nanoparticle incorporation in polyurethane foams: a solution for future antimicrobial materials?, Radu Claudiu Fierascu, Eduard-Marius Lungulescu, Irina Fierascu, Miruna S. Stan, Ionela C. Voinea, Silviu Ionel Dumitrescu. Polymers (2023),
  2. Lungulescu, E.-M.; Fierascu, R.C.; Stan, M.S.; Fierascu, I.; Radoi, E.A.; Banciu, C.A.; Gabor, R.A.; Fistos, T.; Marutescu, L.; Popa, M.; et al. Gamma Radiation-Mediated Synthesis of Antimicrobial Polyurethane Foam/Silver Nanoparticles. Polymers 2024, 16, 1369. https://doi.org/10.3390/polym1610136

Scientific meetings

  1. International Exhibition of Inventions and Innovations “TRAIAN VUIA – 2022 Timisoara, Antimicrobial nanocomposites based on polyurethane foam for biomedical applications, synthesized by radiation assisted technology (PuMA), Radu Claudiu Fierascu, Marius Eduard Lungulescu, Miruna Stan, Toma Fistos, Roxana Ioana Matei (Brazdis), Irina Fierascu (Gold medal, Special award from University of Medicine and Pharmacy V Babeș Timișoara)
  2. Characterization of metal nanoparticles/polyurethane foams for practical applications, Toma Fistos, Roxana Ioana Matei (Brazdis), Anda Maria Baroi, Irina Fierascu, Radu Claudiu Fierascu, Raluca Augusta Gabor, Marius Eduard Lungulescu, Nicoleta Nicula, Miruna Stan, “Priorities of Chemistry for a Sustainable Development” PRIOCHEM XIXth Edition, 11-13 Octombrie 2023, Bucuresti

Book chapters

  1. Fierascu, I., Baroi, A.M., Fistos, T., Brazdis, R.I., Sardarescu (Toma), I.D., Fierascu, R.C. (2022). Bryophytes and the Nanotechnology: Recent Developments and Perspectives. In: Murthy, H.N. (eds) Bioactive Compounds in Bryophytes and Pteridophytes. Reference Series in Phytochemistry. Springer, Cham. https://doi.org/10.1007/978-3-030-97415-2_29-1