G6: Biotechnology & bioanalysis
The 6th Research Group carries out research activities in the field of Biotechnology & Bioanalysis, the research directions being: 1. Biotechnologies for environmental protection and remediation Biodegradation of waste and pollutants Biotechnologies to remedy contamination 2. Agri-food and industrial biotechnologies for obtaining biologically active products Microbial technologies for obtaining substances with antimicrobial properties Pharmaceutical biotechnologies Biotechnologies for obtaining products with uses in the light chemical and food industry (new sources of enzymes) 3. Bioanalysis methods for quality control of products and biotechnological processes in the field of health, environment and agri-food Advanced methods and techniques of analysis, control and quality assurance of biotechnological substances and products Development of sensors, biosensors and immunosensors for the detection of toxic compounds, pollutants and metabolites in the environment and agri-food products. Within the 6th reasearch group, there is a Collection of Microorganisms that contains fungi, yeasts and bacteria, which allows and supports the biotechnological approach of our research activities. Microorganisms have the ability to adapt to a variety of environmental conditions, their versatility making them useful for various biotechnological applications, such as removing pollutants from the environment, bioremediation or transformation into harmless compounds such as carbon dioxide and water. Enriching the collection of microorganisms by isolating them from various sources and maintaining them are of permanent concerns of microbiologists. The 6th research group is a multidisciplinary team, consisting in 2 chemists, 2 biochemists, 2 biologists, 1 engineer and 1 technician (3 CSI, 2 CSII, 2 CSIII; 6 doctors in science). The specialists our group actively participate in: Evaluation of scientific research projects carried out at national (UEFISCDI) and European level (INTAS experts) Review activity as references of specialized magazines from Romania and abroad – Roum. Biotechnol. Letters, Biosensors & Bioelectronics (Elsevier), Food Biotechnology, Sensors, Toxins, Biomachine, Biosensors, Bioelectrochemistry, Biomedical and Environmental Science, etc. Supporting the activity of the Romanian Society of Bioengineering and Biotechnology (SRBB) (www.srbb.ro), an organization affiliated since 1993 to the European Biotechnology Federation Didactic activities carried out in higher education institutions (University of Bucharest, Polytechnic University of Bucharest, etc.). Through Capacity project 49/CP/I/2007, the laboratories of the Biotechnology & Bioanalysis team were arranged according to GLP norms as follows: Microbiology Laboratory (respecting the Rules of Good Laboratory Practice-RBPL regarding the flow of personnel, materials and samples) Laboratory for (BIO) Sensors and optical methods of bioanalysis Laboratory for Separation Methods
Senior Scientist 1st degree, General Manager of INCDCP-ICECHIM
Dr. biochem.
Extension: 102
Senior Scientist 1st degree, Leader of Biotechnology & Bioanalysis Research Group
Dr. Chem.
Extension: 170
Senior Scientist 2nd degree, Deputy leader of Biotechnology & Bioanalysis Research Group
Dr. Chem.
Extension: 144
INNOVATIVE FULLERENOL – HYDROGELS BASED NANOMATERIALS FOR HEALTH DIAGNOSTIC AND CARE APPLICATIONS – FULSENS-GEL
The main objective of the project consists in the development of an innovative nanomaterial, based on combination of the elastic, flexible and resistant hydrogels with functional nanomaterials based on fullerenols
BIOGENIC AMINES DETECTION IN FOOD BASED ON AN INNOVATIVE OPTO-ELECTROSENSITIVE PLATFORM
Scopul principal al proiectului îl constituie dezvoltarea unor platforme opto-electrosensibile, miniaturizate, rentabile și robuste bazate pe un nanomaterial inovator pentru determinarea specifică și sensibilă a aminelor biogene (BAs) din alimente
BioConstrMater
Biotechnological strategies for innovative construction materials incorporating bacterial bioproduct
Marilena-Gabriela Olteanu Zaharie, Nicoleta Radu, Lucia Pirvu, Marinela Bostan, Mariana Voicescu, Mihaela Begea, Mariana Constantin, Catalina Voaides, Narcisa Babeanu and Viviana Roman
Studies Regarding the Pharmaceutical Potential of Derivative Products from Plantain
Plants 2022, 11, 1827. https://doi.org/10.3390/ plants11141827
10.3390/ plants11141827
Verginica Schroder, Nicoleta Radu, Petruta Calina Cornea, Oana Andreia Coman, Lucia Camelia Pirvu, Mohammed Shaymaa Omar Mohammed, Amalia Stefaniu, Lucia Pintilie, Marinela Bostan, Mihai Dan Caramihai et al.
Studies Regarding the Antimicrobial Behavior of Clotrimazole and Limonene
Antibiotics 2022, 11, 1816. https://doi.org/10.3390/ antibiotics11121816
10.3390/ antibiotics11121816
Iuliana Răut, Mariana Constantin, Ionela Petre, Monica Raduly, Nicoleta Radu, Ana-Maria Gurban, Mihaela Doni, Elvira Alexandrescu, Cristi-Andi Nicolae and Luiza Jecu
Highlighting Bacteria with Calcifying Abilities Suitable to Improve Mortar Properties
Materials 2022, 15(20), 7259; https://doi.org/10.3390/ma15207259
10.3390/ma15207259
Narcisa Babeanu, Nicoleta Radu* , Cristina-Emanuela Enascuta, Elvira Alexandrescu, Mihaela Ganciarov , Mohammed Shaymaa Omar Mohammed, Ioana Raluca Suica-Bunghez, Raluca Senin, Magdalina Ursu and Marinela Bostan
Obtaining and Characterizing Composite Biomaterials of Animal Resources with Potential Applications in Regenerative Medicine
Polymers 2022, 14, 3544. https://doi.org/ 10.3390/polym14173544
10.3390/polym14173544
Marinela Bostan, Mirela Mihaila, Georgiana Gabriela Petrica-Matei, Nicoleta Radu, Razvan Hainarosie, Cristian Dragos Stefanescu, Viviana Roman and Carmen Cristina Diaconu
Resveratrol Modulation of Apoptosis and Cell Cycle Response to Cisplatin in Head and Neck Cancer Cell Lines
Int. J. Mol. Sci. 2021, 22, 6322
doi.org/ 10.3390/ijms22126322
Iuliana Raut, Mariana Calin, Zina Vuluga, Florin Oancea, Jenica Paceagiu, Nicoleta Radu, Mihaela Doni , Elvira Alexandrescu, Violeta Purcar, Ana-Maria Gurban, Ionela Petre and Luiza Jecu 1,*
Fungal Based Biopolymer Composites for Construction Materials
Materials 2021, 14, 2906
doi.org/ 10.3390/ma14112906
M Calin, I Raut, ML Arsene, M Doni, AM Gurban, L Jecu
Practical exemples regarding the valorization of cultural heritage through archaeometry studies using nuclear techniques and other scientific methods
Chapter 4. Isolation and identification of microorganisms involved in the biodeterioration of cultural heritage artifacts
ISBN: 978-973-0-27114-0
I Raut, M Calin, ML Arsene, M Doni, AM Gurban, L Jecu
Valorization of cultural heritage through archaeometry studies using nuclear techniques and other scientific methods. General considerations and short literature survey
Chapter 5. Microbial deterioration of textile and wood artifacts
ISBN: 978-973-0-27114-0
Marilena Gabriela Zaharie, Mihai Caramihai, Montserrat Adroguer, Paqui Blánquez, Tom Kuppens and Nicoleta Radu
Virtual Reality and Mixed Reality Education: A Solution for Today’s Education in a Circular Bioeconomy
16th International Symposium “Priorities of Chemistry for a Sustainable Development” PRIOCHEM, Bucharest, Romania, 28–30 October 2020.
Mariana Călin, Iuliana Răut, Ana-Maria Gurban, Mihaela Doni, Nicoleta Radu, Gelu Vasilescu and Luiza Jecu
Assessment of Biological Contamination from Wooden Artifacts of Golesti Museum
16th International Symposium “Priorities of Chemistry for a Sustainable Development” PRIOCHEM, Bucharest, Romania, 28–30 October 2020
Iuliana RĂUT, Mariana CĂLIN, Ana-Maria GURBAN, Luiza CAPRĂ, Mihaela DONI, Nicoleta RADU, Gelu VASILESCU and Luiza JECU
A Biotechnological Process for Valorizing Poultry Feathers through Keratinolytic Cladosporium Isolates
16th International Symposium “Priorities of Chemistry for a Sustainable Development” PRIOCHEM, Bucharest, Romania, 28–30 October 2020.
Naomi Tritean, Mariana Călin, Iuliana Răut, Ana-Maria Gălan, Alexandru Vlaicu, Diana Constantinescu-Aruxandei and Florin Oancea
Extraction of Proteins from Microalgae Using Lytic Enzymes Produced by Trichoderma Strains
16th International Symposium “Priorities of Chemistry for a Sustainable Development” PRIOCHEM, Bucharest, Romania, 28–30 October 2020.
Nicoleta Radu, Narcisa Babeanu, Petruta Cornea, Mariana Calin , Luiza Jecu, Iuliana Raut, Ana Maria Gurban and Mihaela Doni
Painting Degradation from Inside Wooden Churches Achieved in the Period 1750–1850
16th International Symposium “Priorities of Chemistry for a Sustainable Development” PRIOCHEM, Bucharest, Romania, 28–30 October 2020.
Indira Galit, Nicoleta Radu, Ana Aurelia Chirvase , Mihai Dan Caramihai , Montserrat Sarrà, Paqui Blánquez, Tom Kuppens , Charlotte Adriaensens and Narcisa Babeanu
Developments of Tertiary Level Studies in Biotechnologies and Their Applications in Environmental Bioengineering
16th International Symposium “Priorities of Chemistry for a Sustainable Development” PRIOCHEM, Bucharest, Romania, 28–30 October 2020
Ana-Maria Gurban , Petru Epure, Iuliana Răut, Mariana Călin, Nicoleta Radu, Claudia Ninciuleanu, Bogdan Trică, Luiza Jecu, Elvira Alexandrescu and Mihaela Doni
Different Approaches in Designing Sensitive Tools Based on Nanocomposite Materials for Biological Analytes Detection
16th International Symposium “Priorities of Chemistry for a Sustainable Development” PRIOCHEM, Bucharest, Romania, 28–30 October 2020.