National Institute for Research & Development in Chemistry and Petrochemistry

ICECHIM

G6: Biotechnology & bioanalysis

About us

The 6th Research Group carries out research activities in the field of Biotechnology & Bioanalysis, the research directions being: 1. Biotechnologies for environmental protection and remediation  Biodegradation of waste and pollutants  Biotechnologies to remedy contamination 2. Agri-food and industrial biotechnologies for obtaining biologically active products  Microbial technologies for obtaining substances with antimicrobial properties  Pharmaceutical biotechnologies  Biotechnologies for obtaining products with uses in the light chemical and food industry (new sources of enzymes) 3. Bioanalysis methods for quality control of products and biotechnological processes in the field of health, environment and agri-food  Advanced methods and techniques of analysis, control and quality assurance of biotechnological substances and products  Development of sensors, biosensors and immunosensors for the detection of toxic compounds, pollutants and metabolites in the environment and agri-food products. Within the 6th reasearch group, there is a Collection of Microorganisms that contains fungi, yeasts and bacteria, which allows and supports the biotechnological approach of our research activities. Microorganisms have the ability to adapt to a variety of environmental conditions, their versatility making them useful for various biotechnological applications, such as removing pollutants from the environment, bioremediation or transformation into harmless compounds such as carbon dioxide and water. Enriching the collection of microorganisms by isolating them from various sources and maintaining them are of permanent concerns of microbiologists. The 6th research group is a multidisciplinary team, consisting in 2 chemists, 2 biochemists, 2 biologists, 1 engineer and 1 technician (3 CSI, 2 CSII, 2 CSIII; 6 doctors in science). The specialists our group actively participate in:  Evaluation of scientific research projects carried out at national (UEFISCDI) and European level (INTAS experts)  Review activity as references of specialized magazines from Romania and abroad – Roum. Biotechnol. Letters, Biosensors & Bioelectronics (Elsevier), Food Biotechnology, Sensors, Toxins, Biomachine, Biosensors, Bioelectrochemistry, Biomedical and Environmental Science, etc.  Supporting the activity of the Romanian Society of Bioengineering and Biotechnology (SRBB) (www.srbb.ro), an organization affiliated since 1993 to the European Biotechnology Federation  Didactic activities carried out in higher education institutions (University of Bucharest, Polytechnic University of Bucharest, etc.). Through Capacity project 49/CP/I/2007, the laboratories of the Biotechnology & Bioanalysis team were arranged according to GLP norms as follows:  Microbiology Laboratory (respecting the Rules of Good Laboratory Practice-RBPL regarding the flow of personnel, materials and samples)  Laboratory for (BIO) Sensors and optical methods of bioanalysis  Laboratory for Separation Methods

Team

Senior Scientist 1st degree, General Manager of INCDCP-ICECHIM

Dr. biochem.

Extension: 102

Senior Scientist 1st degree, Leader of Biotechnology & Bioanalysis Research Group

Dr. Chem.

Extension: 170

Senior Scientist 2nd degree, Deputy leader of Biotechnology & Bioanalysis Research Group

Dr. Chem.

Extension: 144

Senior Scientist 1st degree

Dr. Sc. HDR

Extension: 171

Senior Scientist 2nd degree

Engineer

Extension: 171

Senior Scientist 3rd degree

Dr. Biology

Extension: 170

Senior Scientist 3rd degree

Dr. Biology

Extension: 170

Technician

Techn.

Extension: 170

ACS

Biologist

Extension: 144

ACS

Dr.chem

Extension: 144

ACS

Chemist

Extension: 144

Research equipment
International projects

INNOVATIVE FULLERENOL – HYDROGELS BASED NANOMATERIALS FOR HEALTH DIAGNOSTIC AND CARE APPLICATIONS – FULSENS-GEL

The main objective of the project consists in the development of an innovative nanomaterial, based on combination of the elastic, flexible and resistant hydrogels with functional nanomaterials based on fullerenols

National projects

BIOGENIC AMINES DETECTION IN FOOD BASED ON AN INNOVATIVE OPTO-ELECTROSENSITIVE PLATFORM

Scopul principal al proiectului îl constituie dezvoltarea unor platforme opto-electrosensibile, miniaturizate, rentabile și robuste bazate pe un nanomaterial inovator pentru determinarea specifică și sensibilă a aminelor biogene (BAs) din alimente

BioConstrMater

Biotechnological strategies for innovative construction materials incorporating bacterial bioproduct

Results
  • Publications
  • Books
  • Conferences
  • Patents
  • Other
Publications

Marilena-Gabriela Olteanu Zaharie, Nicoleta Radu, Lucia Pirvu, Marinela Bostan, Mariana Voicescu, Mihaela Begea, Mariana Constantin, Catalina Voaides, Narcisa Babeanu and Viviana Roman

Studies Regarding the Pharmaceutical Potential of Derivative Products from Plantain

Plants 2022, 11, 1827. https://doi.org/10.3390/ plants11141827

10.3390/ plants11141827

Catalina Voaides, Nicoleta Radu, Elena Birza and Narcisa Babeanu

Medlar—A Comprehensive and Integrative Review

Plants 2021, 10(11), 2344; https://doi.org/10.3390/plants10112344

10.3390/plants10112344

Verginica Schroder, Nicoleta Radu, Petruta Calina Cornea, Oana Andreia Coman, Lucia Camelia Pirvu, Mohammed Shaymaa Omar Mohammed, Amalia Stefaniu, Lucia Pintilie, Marinela Bostan, Mihai Dan Caramihai et al.

Studies Regarding the Antimicrobial Behavior of Clotrimazole and Limonene

Antibiotics 2022, 11, 1816. https://doi.org/10.3390/ antibiotics11121816

10.3390/ antibiotics11121816

Mariana Constantin, Iuliana Raut, Ana-Maria Gurban, Mihaela Doni, Nicoleta Radu, Elvira Alexandrescu and Luiza Jecu

Exploring the Potential Applications of Paecilomyces lilacinus 112

Appl. Sci. 2022, 12, 7572. https://doi.org/ 10.3390/app12157572

10.3390/app12157572

Iuliana Răut, Mariana Constantin, Ionela Petre, Monica Raduly, Nicoleta Radu, Ana-Maria Gurban, Mihaela Doni, Elvira Alexandrescu, Cristi-Andi Nicolae and Luiza Jecu

Highlighting Bacteria with Calcifying Abilities Suitable to Improve Mortar Properties

Materials 2022, 15(20), 7259; https://doi.org/10.3390/ma15207259

10.3390/ma15207259

Books

Calin M; Raut I.; Gurban A.-M.; Doni M.; Radu N.; Jecu L.

Archaeometrical study of selected objectives from Golesti Museum of Viticulture and Pomiculture

Chapter5: Microbial contamination of wooden cultural heritage artifacts of selected objectives from Golesti Museum

ISBN978-619-91466-1-3

Radu N.; Babeanu N.; Cornea P.; Calin M.; Jecu L.; Gurban A.M; Doni, M;

Archaeometrical study of selected objectives from Golesti Museum of Viticulture and Pomiculture

Chapter 4:Paintings characteristics from inside of wooden church achieved in the period 1750-1850

ISBN 978-619-91466-1-3

M Calin, I Raut, ML Arsene, M Doni, AM Gurban, L Jecu

Practical exemples regarding the valorization of cultural heritage through archaeometry studies using nuclear techniques and other scientific methods

Chapter 4. Isolation and identification of microorganisms involved in the biodeterioration of cultural heritage artifacts

ISBN: 978-973-0-27114-0

I Raut, M Calin, ML Arsene, M Doni, AM Gurban, L Jecu

Valorization of cultural heritage through archaeometry studies using nuclear techniques and other scientific methods. General considerations and short literature survey

Chapter 5. Microbial deterioration of textile and wood artifacts

ISBN: 978-973-0-27114-0

F. Oancea, I. Raut, T.E .Sesan, M. Doni, M. Popescu, V. Zamfiropol-Cristea, L. Jecu

Trichoderma spp. – applications in agriculture and horticulture

Chapter 8 – Formulation of the Multifunctional Trichoderma Strains

ISBN 978-606-16-0900-0

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Conferences

Marilena Gabriela Zaharie, Mihai Caramihai, Montserrat Adroguer, Paqui Blánquez, Tom Kuppens and Nicoleta Radu

Virtual Reality and Mixed Reality Education: A Solution for Today’s Education in a Circular Bioeconomy

16th International Symposium “Priorities of Chemistry for a Sustainable Development” PRIOCHEM, Bucharest, Romania, 28–30 October 2020.

Mariana Călin, Iuliana Răut, Ana-Maria Gurban, Mihaela Doni, Nicoleta Radu, Gelu Vasilescu and Luiza Jecu

Assessment of Biological Contamination from Wooden Artifacts of Golesti Museum

16th International Symposium “Priorities of Chemistry for a Sustainable Development” PRIOCHEM, Bucharest, Romania, 28–30 October 2020

Iuliana RĂUT, Mariana CĂLIN, Ana-Maria GURBAN, Luiza CAPRĂ, Mihaela DONI, Nicoleta RADU, Gelu VASILESCU and Luiza JECU

A Biotechnological Process for Valorizing Poultry Feathers through Keratinolytic Cladosporium Isolates

16th International Symposium “Priorities of Chemistry for a Sustainable Development” PRIOCHEM, Bucharest, Romania, 28–30 October 2020.

Naomi Tritean, Mariana Călin, Iuliana Răut, Ana-Maria Gălan, Alexandru Vlaicu, Diana Constantinescu-Aruxandei and Florin Oancea

Extraction of Proteins from Microalgae Using Lytic Enzymes Produced by Trichoderma Strains

16th International Symposium “Priorities of Chemistry for a Sustainable Development” PRIOCHEM, Bucharest, Romania, 28–30 October 2020.

Nicoleta Radu, Narcisa Babeanu, Petruta Cornea, Mariana Calin , Luiza Jecu, Iuliana Raut, Ana Maria Gurban and Mihaela Doni

Painting Degradation from Inside Wooden Churches Achieved in the Period 1750–1850

16th International Symposium “Priorities of Chemistry for a Sustainable Development” PRIOCHEM, Bucharest, Romania, 28–30 October 2020.

Patents

Oancea Florin, Velea Sanda, Popescu Mariana, Răut Iuliana

Process for conditioning biostimulating microorganisms for plants, in the form of an effervescent tablet

131927/30.08.2019

F Oancea, I Raut, TE Sesan, M Doni, M Popescu, L Jecu

Procedure for selecting consortia of microorganisms for the treatment of plant material

131224B1/2019

F Oancea, I. Raut, Abraham Beata, Szabolcs Lanyi Stefan, M Doni, L Jecu

High yield process for the selection of consortia of microorganisms with action to stimulate cultivated plants

131225

Oancea F, Sesan T E, M Doni, Raut I, Vlăsceanu G A, Negru G. L Jecu

Silicium-based biostimulating composition for foliar application

3/2/30.01.2019

F Oancea, I Raut, TE Sesan, M Doni, M Popescu, L Jecu

Procedure for selecting consortia of microorganisms that release and solubilize biosilicium from plant material

131828B1/2019

Other

R.M. Ion; N. Ion; L. Iancu; N. Radu

Silver Medal awarded to Patent request to EUROINVENT, 11th Edition, European Exhibition of Creativity and Innovation, May 18, 2019, Iasi, Romania.

R.M. Ion, N. Ion, L.Iancu, N. Radu

Gold Medal awarded to Patent request 17th edition of PROINVENT, March 20-22, 2019, Cluj Napoca, Romania