National Institute for Research & Development in Chemistry and Petrochemistry


G9: Heterogeneous systems

About us

The “Heterogeneous Systems” Group ( has a prestigious activity in the polymerization field, evidenced by numerous scientific papers published in journals with high impact factor. The group aims is to develop activities of creation, selection and manufacture of nanocomposite materials, technologies and applications of the nanomaterials (medical, environmental and electronic devices). The members of Heterogeneous Systems Group are scientists with well-established national and international scientific recognition, together with many young researchers, most of them being specialized in prestigious research laboratories. In 2012, following a process of institutional evaluation and certification, our group received a rating of Excellent from the committee of international experts. The group has a good research activity in few fundamental and applicative projects supported by National Research, Development and Innovative Program – PNCDI. At European level, our group has coordinated a project with acronym ENPONA within FP6-SSA programme and participated as a beneficiary in the projects HARCANA (programme FP7-Large) and PRONACOM (FP5-IP programme), priority Nanosciences and Nanotechnologies. Also, our group was involved in bilateral programs with universities and institutes from France, Czech Republic, Greece, Spain and Italy. In collaboration with other universities, the Heterogeneous Systems Group has a good experience in educational program at undergraduate, postgraduate and doctoral level and the experience of their scientists offer good conditions to organize training in many specialties. Due to its location, in the middle of the academic and high-technology industrial environment, our group has a good collaboration with many universities and institutes, which allow offering complementary expertise in different research fields. Express of Interest Fields: – Polymer-inorganic hybrids obtained by sol-gel process and/or melting intercalation processing – Polymer-inorganic functional nanoparticles obtained in disperse media – Hybrid nanocomposites obtained by Layer-by-Layer polyelectrolyte deposition – Polymeric nanoparticles and thin films for biomedical applications – Hybrid magnetic-polymer nanoparticles for drug delivery systems and biosensors – Emulsion and microemulsion polymerization with functional monomers – Multifunctional polymer electrolytes – Core-shell micro- and nanoparticles – Customer designed synthesis for new biocompatible polymers – Micro- and nanoparticles with controlled properties – Specific, high technology, analyses and characterizations for polymer nanoparticles.


Team Leader
Senior researcher II degree

Dr. Eng.

Extension: 107

Team Viceleader
Senior researcher I degree

Dr. Eng.

Extension: 164

Senior researcher I degree

Dr. Eng.

Extension: 132

Senior researcher III degree

Dr. Chem.

Extension: 132

Senior researcher III degree

Extension: 156


Extension: 107

Research equipment
International projects
National projects
  • Publications
  • Books
  • Conferences
  • Patents
  • Other

R. Ianchis, C.M. Ninciuleanu, I.C. Gifu, E. Alexandrescu, C.L. Nistor, S. Nitu, C. Petcu

Hydrogel-clay nanocomposites as carriers for controlled release

Curr.Med.Chem., 2020, 27(6), 919-954. DOI: 10.2174/0929867325666180831151055


I. Raut, M. Calin, Z. Vuluga, E. Alexandrescu, M.L. Arsene, V. Purcar, C.A. Nicolae, A.M. Gurban, M. Doni, L. Jecu

Comparative Study on the Behavior of Virgin and Recycled Polyolefins-Cellulose Composites in Natural Environmental Conditions

J.Compos.Sci., 2019, 3(2), 60-74. DOI: 10.3390/jcs3020060


I.C. Gifu, M.E. Maxim, L.O. Cinteza, M. Popa, L. Aricov, A.R. Leonties, M. Anastasescu, D.F. Anghel, R. Ianchis, C.M. Ninciuleanu, S.G. Burlacu, C.L. Nistor, C. Petcu

Antimicrobial Activities of Hydrophobically Modified Poly(Acrylate) Films and Their Complexes with Different Chain Length Cationic Surfactants

Coatings, 2019, 9(4), 244-256. DOI: 10.3390/coatings9040244


L. Capra, M. Manolache, I. Ion, R. Stoica, G. Stinga, S.M. Doncea, E. Alexandrescu, R. Somoghi, M.R. Calin, I. Radulescu, G.R. Ivan, M. Deaconu, A.C. Ion

Adsorption of Sb (III) on Oxidized Exfoliated Graphite Nanoplatelets

Nanomaterials, 2018, 8(12), 992. DOI: 10.3390/nano8120992


M. Mateescu, S.M. Doncea, I. Raut, C.L. Nistor, I.C. Bujanca

Synthesis and biomedical application of hydroxyapatite as carrier for loading and controlled delivery of antibiotics

Rev.Chim.(Bucharest), 2018, 69(12), 3400-3405.


L.O. Cinteza, C. Scomoroscenco, S. Voicu, C.L. Nistor, S.G. Nitu, B. Trica, M.L. Jecu, C. Petcu

Chitosan-Stabilized Ag Nanoparticles with Superior Biocompatibility and Their Synergistic Antibacterial Effect in Mixtures with Essential Oils

Nanomaterials (Basel), 2018, 8(10), 826. DOI: 10.3390/nano8100826


L.O. Cinteza, S.N. Voicu, M. Popa, L. Marutescu, S. Nitu, R. Somoghi, C.L. Nistor, C. Petcu

Rational design of silver nanoparticles with reduced toxicity and enhanced antimicrobial activity

Rom.Biotechnol.Lett., 2018, 23(4), 13878-13886.


C.E. Enascuta, E. Stepan, E.E. Oprescu, A. Radu, E. Alexandrescu, R. Stoica, D.G. Epure, M.D. Niculescu

Microencapsulation of essential oils

Rev.Chim.(Bucharest), 2018, 69(7), 1612-1615.


C. Anastasescu, S. Preda, A. Rusu, D. Culita, G. Plavan, S. Strungaru, J.M. Calderon-Moreno, C. Munteanu, C. Gifu, M. Enache, R. Socoteanu, D. Angelescu, M. Anastasescu, M. Gartner, I. Balint, M. Zaharescu

Tubular and Spherical SiO2 Obtained by Sol Gel Method for Lipase Immobilization and Enzymatic Activity

Molecules, 2018, 23(6), 1362. DOI: 10.3390/molecules23061362


A.N. Frone, D.M. Panaitescu, I. Chiulan, C.A. Nicolae, A. Casarica, A.R. Gabor, R. Trusca, C.M. Damian, V. Purcar, E. Alexandrescu, P.O. Stanescu

Surface Treatment of Bacterial Cellulose in Mild, Eco-Friendly Conditions

Coatings, 2018, 8(6), 221. DOI: 10.3390/coatings8060221



T. Munteanu, C.M. Ninciuleanu, I.C. Gifu, B. Trica, E. Alexandrescu, A.R. Gabor, S. Preda, C. Petcu, C.L. Nistor, S.G. Nitu, R. Ianchis

The Effect of Clay Type on the Physicochemical Properties of New Hydrogel Clay Nanocomposites

In: Current Topics in the Utilization of Clay in Industrial and Medical Applications, Publisher IntechOpen, Chapter 8,

ISBN: 978-1-78923-728-3


R. Ianchiș, I.C. Gîfu, C.M. Ninciuleanu, E. Alexandrescu, C. Petcu, C.L. Nistor, S. Nițu

Patent Request – Composition based on clay composite hydrogels and process for their preparation


R. Marinescu, I. Antoniac, C. Petcu, D. Lăptoiu

Patent – Knee Brace with Magnets

RO 128699 B1/2017

C.L. Nistor, R. Ianchiș, F. Oancea, M.L. Jecu, I. Răuț, D. Donescu

Patent – Process for essential oils encapsulation into mesoporous silica systems and for their application as plant biostimulants

WO/2017/091096 (PCT/RO 2016-0025)

S.A. Gârea, A.I. Voicu, M.A. Pandele, H. Iovu, A. Sârbu, C.L. Nistor, E. Vasile, C. Păduraru

Patent – Process for obtaining heterostructured porous clays using hydrophilic polyetheramines

RO 132571 B1/2016

S.A. Gârea, A.I. Voicu, A. Ghebaur, H. Iovu, A. Sârbu, C.L. Nistor, E. Vasile, C. Păduraru

Patent – Method of obtaining heterostructured porous clays using haloisite

RO 132550 B1/2016

C. Petcu, L.C. Nistor, C.I. Spătaru, V. Purcar, L.O. Cinteză, M.C. Rusu

Patent Request – Coating process for a translucent or transparent thermoplastic material


C.L. Nistor, R. Ianchiș, F. Oancea, M.L. Jecu, I. Răuț, D. Donescu

Patent – Process for producing capsules based on essential oils and method of administration

RO 131823 B1/2015

E.D. Teodor, V. Lazăr, M. Mihalache, C. Petcu

Patent – Nanostructured Biomaterial Based on Magnetic Nanoparticles and Hydrogel

RO 122017 B1/2008