National Institute for Research & Development in Chemistry and Petrochemistry

ICECHIM

G4: Bioproducts

About us

Team E4

Testing cytocompatibility of bioproducts and formulations with an automated fluorescence microscope
Team

Senior Researcher Ist degree, Team Leader

PhD Habil. Biochem.

Extension: 103

Senior Researcher Ist degree, Deputy Team Leader

PhD Chem.

Extension: 111

Senior Researcher Ist degree

PhD Biochem.

Extension: 128

Senior Researcher IIIrd degree

PhD Eng.

Extension: 169

Senior Researcher IIIrd degree

PhD Phys.

Extension: 113

Senior Researcher IIIrd degree

PhD Eng.

Extension: 122

Senior Researcher IIIrd degree

PhD Chem.

Extension: 122

Senior Researcher IIIrd degree

PhD Eng.

Extension: 106

Scientific Researcher

PhD Biochem.

Extension: 106

Scientific Researcher

PhD Biochem.

Extension: 106

Scientific Researcher, PhD Stud.

M. Sc. Eng.

Extension: 128

Scientific Researcher, PhD Stud.

M. Sc. Chem.

Extension: 122

Scientific Researcher, PhD Stud.

M. Sc. Chem.

Extension: 106

Scientific Researcher, PhD Stud.

M. Sc. Biotech. Eng.

Extension: 106

Scientific Research Assistant

M. Sc. Biol.

Extension: 122

Scientific Research Assistant

M. Sc. Vet Med.

Extension: 106

Technician Tr. II

Ms.

Extension: 169

Research equipment
International projects

STIM4+

Integrated use of the next generation plant biostimulants for an enhanced sustainability of field vegetable high residue farming systems

National projects

Technological modular and interconnected platforms for an optimized conversion in market-demanded bioproducts of side-streams specific to Romanian bioeconomy

The objective of the project is to provide the conversion of side-streams resulted from the Romanian bioeconomy into (bio)products and (bio)materials with high added value

Research on sustainable technologies for obtaining and valorising innovative functional ingredients and foods, for nutritional equilibration of the modern consumer’s diet

The objective of the project is the valorisation by sustainable technologies of side-streams from the food industry to obtain ingredients or innovative foods which combine various vegetal and/or animal sources

Better harnessing of Trichoderma biotechnological potential for biorefinery and as plant biostimulants by controlled development and biosynthesis

Project TOTAL aims to investigate and integrate abiotic modulation and epigenetic control of Trichoderma strains within the context of Trichoderma interactions with biomass and living matter, for better harnessing of Trichoderma potential

Biogenic nano-system for targeted delivery of bioactive ingredients on dysbiosis biofilm involved in gingivitis and periodontitis – BioNanoGum

Biogenic nano-system for targeted delivery of bioactive ingredients on dysbiosis biofilm involved in gingivitis and periodontitis

Superior valorisation of bioresources through advanced (bio)chemical eco-technologies

The objective of the project is to valorise the side-streams from agriculture and food industry and to obtain products with high added value, such as food supplements and plant biostimulants.

Biosynthesis of selenium nanoparticles with amplified bioactivity

The object of the project is to obtain selenium nanoparticles bio-synthesized by microorganisms, especially benefial filamentous fungi, with applications in agronomical biofortification.

Results
  • Publications
  • Books
  • Conferences
  • Patents
  • Other
Publications

Ioana Popa-Tudor, Naomi Tritean, Ștefan-Ovidiu Dima, Bogdan Trică, Marius Ghiurea, Anisoara Cimpean, Florin Oancea, Diana Constantinescu-Aruxandei

Kombucha Versus Vegetal Cellulose for Affordable Mucoadhesive (nano)Formulations

Gels 2025, 11(1), 37

001403836600001

Livia Teodora Ciobanu, Victoria Bînzari, Ștefan-Ovidiu Dima, Ileana Cornelia Farcasanu, Florin Oancea, Diana Constantinescu-Aruxandei

The Clothes Matter—Exploiting Agronomical Functions of Trichogenic Selenium Nanoparticles Sharing Activities with Biological Systems Wherein (Were) Formed

Agronomy 2024, 14(1), 190

001151978800001

Ioana-Alexandra Bala, Alina Nicolescu, Florentina Georgescu, Florea Dumitrascu, Anton Airinei, Radu Tigoianu, Emilian Georgescu, Diana Constantinescu-Aruxandei, Florin Oancea, Calin Deleanu

Synthesis and Biological Properties of Fluorescent Strigolactone Mimics Derived from 1,8-Naphthalimide

Molecules 2024, 29(10), 2283

001231288900001

Naomi Tritean, Bogdan Trică, Ştefan-Ovidiu Dima, Luiza Capră, Raluca-Augusta Gabor, Anisoara Cimpean, Florin Oancea, Diana Constantinescu-Aruxandei

Mechanistic insights into the plant biostimulant activity of a novel formulation based on rice husk nanobiosilica embedded in a seed coating alginate film

Frontiers in Plant Sciences 2024, 15:1349573

001237852100001

Steven J Brooks, Tânia Gomes, Ana Catarina Almeida, Maria Christou, Congying Zheng, Sergey Shaposhnikov, Daria G Popa, Florentina Georgescu, Florin Oancea

An ecotoxicological assessment of a strigolactone mimic used as the active ingredient in a plant biostimulant formulation

Ecotoxicology and Environmental Safety, Volume 275, 15 April 2024, 116244

001224554700001

Eliza Gabriela Brettfeld, Daria Gabriela Popa, Tănase Dobre, Corina Ioana Moga, Diana Constantinescu-Aruxandei, Florin Oancea

CO2 Capture Using Deep Eutectic Solvents Integrated with Microalgal Fixation

Clean Technologies 2023, 6(1), 32-48

001191918900001

Daria Gabriela Popa, Florentina Georgescu, Florea Dumitrascu, Sergiu Shova, Diana Constantinescu-Aruxandei, Constantin Draghici, Lucian Vladulescu, Florin Oancea

Novel Strigolactone Mimics That Modulate Photosynthesis and Biomass Accumulation in Chlorella sorokiniana

Molecules 2023, 28(20)

001099476300001

Luminița Dimitriu, Diana Constantinescu-Aruxandei, Daniel Preda, Andra-Lavinia Nichițean, Cristian-Andi Nicolae, Victor Faraon, Marius Ghiurea, Mihaela Ganciarov, Narcisa Elena Băbeanu, Florin Oancea

Honey and its biomimetic deep eutectic solvent modulate the antioxidant activity of polyphenols

Antioxidants 2022, 11(11), 2194; https://doi.org/10.3390/antiox11112194

10.3390/antiox11112194

Diana Constantinescu-Aruxandei, Carmen Lupu, Florin Oancea

Siliceous Natural Nanomaterials as Biorationals—Plant Protectants and Plant Health Strengtheners

Agronomy

10.3390/agronomy10111791

Elisaveta Apostolova, Paolina Lukova, Alexandra Baldzhieva, Plamen Katsarov, Mariana Nikolova, Ilia Iliev, Lyudmil Peychev, Bogdan Trica, Florin Oancea, Cédric Delattre, Vesela Kokova

Immunomodulatory and Anti-Inflammatory Effects of Fucoidan: A Review

Polymers

10.3390/polym12102338

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Books
Conferences

Andreea-Luiza MIRT, Alin Cristian Nicolae VINTILA, Daria Gabriela POPA, Mălina AVRAM DEȘLIU, Alexandru VLAICU, Simona-Bianca GHIMIȘ, Diana CONSTANTINESCU ARUXANDEI, Florin OANCEA, Gabriel VASILIEVICI

BIOCHAR BY PYROLYSIS OF SOLID DIGESTATE RESULTING FROM ANAEROBIC DIGESTION OF SPENT PLEUROTUS SUBSTRATE

International Symposium Priorities of chemistry for a sustainable development PRIOCHEM XX, 2024

Mihaela CILTEA-UDRESCU, Mălina AVRAM-DEȘLIU, Alin Cristian Nicolae VINTILA, Daria Gabriela POPA, Alexandru VLAICU, Anca PAULENCO, Diana CONSTANTINESCU ARUXANDEI, Florin OANCEA, Gabriel VASILIEVICI.

POTENTIAL OF SPENT PLEUROTUS SUBSTRATE FOR BIOMETHANE PRODUCTION

International Symposium Priorities of chemistry for a sustainable development PRIOCHEM XX, 2024

Ecaterina-Andreea CONSTANTIN, Oana-Romina BOTORAN, Florentina MATEI, Diana CONSTANTINESCU-ARUXANDEI, Florin OANCEA.

OPTIMIZING FERMENTATION PROCESSES: VALORIZATION OF BY-PRODUCTS IN A NEW APPROACH FOR PRODUCTS IN THE FOOD INDUSTRY

International Symposium Priorities of chemistry for a sustainable development PRIOCHEM XX, 2024

Livia Teodora Ciobanu, Luminița Dimitriu, Ileana Cornelia Farcasanu, Diana Constantinescu-Aruxandei, Florin Oancea.

CALLOGENESIS AS AN IN VITRO MODEL FOR INNOVATIVE BIOSTIMULANTS ASSAYS

International Symposium Priorities of chemistry for a sustainable development PRIOCHEM XX, 2024

Mălina DEȘLIU AVRAM, Ecaterina Andreea CONSTANTIN, Diana CONSTANTINESCU ARUXANDEI, Florin OANCEA.

ANALYSIS OF POLYPHENOLS AND ANTIOXIDANT ACTIVITY OBTAINED FROM A TWO- STEPS EXTRACTION OF APPLE POMACE

International Symposium Priorities of chemistry for a sustainable development PRIOCHEM XX, 2024

Naomi TRITEAN, Luminița DIMITRIU, Ștefan-Ovidiu DIMA, Marius GHIUREA, Bogdan TRICĂ, Cristian- Andi NICOLAE, Ionuț MORARU, Alina NICOLESCU, Anisoara CIMPEAN, Florin OANCEA, Diana CONSTANTINESCU-ARUXANDEI.

ANTI-INFLAMMATORY AND ANTIMICROBIAL NANOFORMULATION BASED ON CHITOSAN GRAFTED WITH FERULIC ACID, NANOCELLULOSE AND SELENIUM NANOPARTICLES

International Symposium Priorities of chemistry for a sustainable development PRIOCHEM XX, 2024

Luminița Dimitriu, Diana Constantinescu-Aruxandei, Daniel Preda, Andra-Lavinia Nichițean, Cristian-Andi Nicolae, Victor Alexandru Faraon, Marius Ghiurea, Mihaela Ganciarov, Narcisa Elena Băbeanu, Florin Oancea

ANTIOXIDANT ADVENTURE: UNRAVELLING HOW RASPBERRY AND HONEYSUCKLE EXTRACTS INTERACT WITH HONEY AND ITS DEEP EUTECTIC FEATURES.

International Congress on Bee Sciences – Icbees, IIIrd edition, Turkey, 24-26 April 2024

Tritean N., Dima Ș.-O., Trică B., Stoica R., Ghiurea M., Moraru I., Cimpean A., Oancea F., Constantinescu-Aruxandei D.

CYTOCOMPATIBLE AND ANTIOXIDANT SELENIUM-FORTIFIED BEVERAGE PRODUCED BY KOMBUCHA FERMENTATION WITH POLLEN

International Congress on Bee Sciences – Icbees, IIIrd edition, Turkey, 24-26 April 2024

Andreea Ecaterina CONSTANTIN, Naomi TRITEAN, Florentina MATEI, Nikolaos TRIVYZAS, Florin OANCEA, Diana CONSTANTINESCU-ARUXANDEI

ENHANCING NUTRITIONAL VALUE AND FLAVOUR PROFILE: MICROAEROPHILIC FERMENTATION OF BEE POLLEN FOR A NOVEL FUNCTIONAL BEVERAGE

International Congress on Bee Sciences – Icbees, IIIrd edition, Turkey, 24-26 April 2024

Patents

Oancea F., Constantinescu Aruxandei D., Bala I., Bărbieru O.–G., Dimitriu L., Tritean N.

SEQUENTIAL SIMULTANEOUS SACCHARIFICATION AND FERMENTATION PROCESS FOR PREPARING 2,3 BUTANEDIOL FROM LIGNOCELLULOSIC MATERIAL

RO135020B1 / 2025-01-30

Oancea F., Constantinescu-Aruxandei D., Bărbieru O. G., Dimitriu L., Tritean N.

BIOSTIMULANT FOR PLANTS BASED ON SYNERGIZED HYDROPHOBINS

RO134165B1 / 2024-07-30

Oancea F., Constantinescu Aruxandei D., Nicolae C. V., Negoi A., Mihăilă E. G.

EUTECTIC SOLVENTS WITH LOW TOXICITY FOR PLANTS

RO135022B1 / 2024-06-28

Oancea F., Constantinescu-Aruxandei D., Bărbieru O., Dimitriu L., Tritean N.

PROCESS FOR PREPARING BIO-ACTIVE PROTEINS AND AMPHIPHILIC PROTEINS FROM LIGNOCELLULOSIC MUSHROOM CULTIVATION SPENT SUBSTRATE

RO134217B1 / 2024-05-30

Oancea F., Constantinescu-Aruxandei D., Deşliu-Avram M., Zamfiropol-Cristea V.

PROCESS FOR SELECTION OF ELICITORS STIMULATING RADICULAR EXO-SIGNAL GENERATION

RO134164B1 / 2024-03-29

Oancea F., Constantinescu-Aruxandei D., Dima Ştefan O., Zamfiropol-Cristea V.

PROCESS FOR PREPARING ORGANO-MINERAL FOLIAR FERTILIZERS OF HIGH FOLIAR PENETRATION

RO133977B1 / 2024-03-29

Oancea F., Constantinescu-Aruxandei D., Călin M., Răut I

PROCESS FOR PREPARING STABLE SUSPENSIONS OF SILICA AND SELENIUM NANOPARTICLES

RO133904B1 / 2023-11-29

Oancea F., Constantinescu-Aruxandei D., Dimitriu L., Lupu C., Șomoghi R., Ghiurea M.

FILM-FORMING COMPOSITION WITH FOLIAR APPLICATION, BASED ON NATURAL SILICON NANOMATERIALS AND PROCESS FOR APPLYING THE SAME

RO135626B1 / 2023-08-30

Oancea F., Constantinescu-Aruxandei D., Lupu C.

COMBINED FODDER WITH LOW RISK OF MYCOTOXIN CONTAMINATION AND PROCESS FOR PREPARING THE SAME

RO135248B1 / 2023-06-30

Oancea F., Cornea P.C., Voaideş C.M. Răut I., Boiu-Sicuia O.A., Constantinescu-Aruxandei D., Doni M., Jecu M.L.

MULTIPURPOSE MICROBIAL CONSORTIUM FOR SOLUBILIZING PHYTO-SILICON AND PROCESS FOR USING THE SAME

RO133468B1 / 2023-03-30

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Other

Naomi TRITEAN

Naomi Tritean defended her PhD Thesis entitled “COMPLEX MUCOADHESIVE BIONANOSYSTEM FOR DEVELOPMENT LIMITATION OF GUM DISBIOTIC BIOFILM” and obtained Summa cum Laude, at Bucharest University, Faculty of Biology, on November 8th, 2024. Congratulations, Naomi!

Naomi TRITEAN, Luminița DIMITRIU, Ștefan-Ovidiu DIMA, Marius GHIUREA, Bogdan TRICĂ, Cristian- Andi NICOLAE, Ionuț MORARU, Alina NICOLESCU, Anisoara CIMPEAN, Florin OANCEA, Diana CONSTANTINESCU-ARUXANDEI

Naomi Tritean and team were awarded for the work “ANTI-INFLAMMATORY AND ANTIMICROBIAL NANOFORMULATION BASED ON CHITOSAN GRAFTED WITH FERULIC ACID, NANOCELLULOSE AND SELENIUM NANOPARTICLES” with an open-access support voucher for publication in Gels (MDPI, 300 CHF) at the XXth edition of PRIOCHEM (18th October 2024).

Ioana-Alexandra BALA

Ioana-Alexandra Bala defended her PhD Thesis in Biotechnologies entitled ”PLANT BIOSTIMULANTS BASED ON (BIO)MIMICS OF STRIGOLACTONES” and obtained Summa cum Laude, at University of Agronomical Sciences and Veterinary Medicine, Faculty of Biotechnology, Bucharest, on October 11th, 2024. Congratulations, Ioana!

Livia Teodora CIOBANU, Diana CONSTANTINESCU-ARUXANDEI, Marius GHIUREA, Bogdan TRICA, Florin OANCEA, Ileana Cornelia FARCASANU

Livia Teodora Ciobanu and team were awarded with The Romanian Chemistry Society award for the work “SODIUM SELENITE TRIGGERS CALCIUM-DEPENDENT RESPONSES IN SACCHAROMYCES CEREVISIAE CELLS” at the exploratory Workshop NeXT-Chem, VIth Edition, 2024.

Luminița DIMITRIU

Luminița Dimitriu defended her PhD Thesis entitled “PRODUCTION AND UTILIZATION OF PLANT EXTRACTS WITH ANTIMICROBIAL AND ANTIOXIDANT EFFECT” and obtained Summa cum Laude, at University of Agronomical Sciences and Veterinary Medicine, Faculty of Biotechnology, Bucharest, on December 18th, 2023. Congratulations, Luminița!